Correction to: Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
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چکیده
منابع مشابه
Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
BACKGROUND Metastatic malignant melanoma is one of the most aggressive malignancies and its treatment remains challenging. Recent studies demonstrate that the melanoma metastasis has correlations with the heightened activations of protein kinase C ζ (PKCζ) and cyclooxygenase-2 (COX-2) signaling pathways. Targeted inhibitions for PKCζ and COX-2 have been considered as the promising strategies fo...
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Cyclooxygenase-2 (COX-2) inhibitors constitute a new group of non-steroidal anti-inflammatory drugs (NSAIDs) which, at recommended doses, block prostaglandin production by cyclooxygenase-2, but not by cyclooxygenase-1. Two COX-2 inhibitors are currently available in Australia--celecoxib, which is taken twice daily, and rofecoxib, which is taken once daily. Both drugs act rapidly in providing pa...
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ژورنال
عنوان ژورنال: Journal of Experimental & Clinical Cancer Research
سال: 2021
ISSN: 1756-9966
DOI: 10.1186/s13046-021-01885-y